The Science Behind COVID-19 Vaccines

Larry A. Law

It wasn't that long ago that the term 'mRNA' was relegated to scientific research papers. Normal people didn't talk about science in that kind of detail. However, we were vaguely aware that there was promising research that might allow scientists to teach cells to create a glycoprotein; this in turn would initiate an immune response against a specific pathogen and cure a dreaded disease. But what a turn of events we've seen in the last few years with the advent of the hyped-up Pfizer and Moderna COVID-19 mRNA vaccines. I am basing this blog article on a stellar article written by Klaus Steger, Ph.D. My hope is to overview (although I rely heavily on his article) some of the disquieting facts he points out that undermine this once hopeful technology.

It's Not Even mRNA—It's modRNA

RNA-based vaccine technology uses modified RNA (modRNA), not mRNA. mRNA is so fragile that the human immune system will destroy it within minutes. The current technology used by Pfizer, Moderna, and all other producers of mRNA vaccines in the pipeline (yes, there are lots of them coming!) utilize altered, stabilized mRNA which is called modRNA. Vaccines based on modified RNA are not traditional vaccines. They are gene-based therapies which force healthy cells to produce a synthetic, viral glycoprotein completely foreign to the cell's DNA instruction set. 

T and B Cells

When you are infected naturally by a virus or get a conventional vaccine, your immune system identifies virus-specific antigens from active or inactivated virus particles. The two main types of adaptive immune cells, T and B cells, behave differently. T cells identify infected cells and start apoptosis (the cell-killing process), while B cells produce antibodies that bind to the virus and prevent further infection of other cells. The antigens on cells are glycoproteins on the surface of each virus. Your immune system can memorize more than one of them. When the virus mutates and some of these glycoproteins change, your immune system can still recognize and kill them. This is called cross-immunity. This makes natural immunity hundreds of times more powerful than vaccine-induced immunity could ever hope to be. Respiratory diseases (like colds, flu, COVID-19, etc.) are stopped by the first natural barrier, the mucous membrane on the epithelial cells (surface cells) of the nose, throat, mouth, and digestive tract. Unfortunately, this barrier gets bypassed when an injection is administered. 

Injections of modRNA—Genetic Manipulation of Healthy Cells

To protect modRNA from immediate destruction by the immune system, the modified RNA is packaged in lipid (fatty) nanoparticles (LNPs). Because they are so small, they penetrate the glycocalyx (cell membrane), thereby bypassing the normal, regulatory glycoproteins that guard the cell and govern what is allowed to come into the cell. The modRNA-based injections penetrate the protective glycocalyx and force the cell to follow the instructions in the modRNA. COVID-19 vaccines code for the original Wuhan version of the spike glycoprotein called SARS-CoV-2. The cell creates numerous versions of this synthetic glycoprotein and places them on the outside of the glycocalyx. There they serve as the target for immune system generation of neutralizing antibodies. That's the theory. Unfortunately, the actual mechanism has lots of operational problems.

Problem: Antibody-Dependent Enhancement

Besides the shot helping the body create the desired COVID-19 neutralizing antibodies, non-neutralizing antibodies can be generated. This unfortunate outcome results in something called antibody-dependent enhancement (ADE). This process allows endocytosis ​(encapsulation or swallowing) of virus-antibody-complexes into the host's immune cells (macrophages), causing the immune system defenses to weaken. The end result is that the person's body becomes MORE susceptible to illness when follow-up and booster injections are administered. 

Problem: Friend or Foe

The synthetic spike glycoprotein, artificially produced by the cell, now sits out on the glycocalyx and acts as a label. This transforms the cell from friend of the body to an enemy. This causes the immune system to begin destruction of that cell via the process of apoptosis. 

Problem: The Shot-Induced Reaction is Much Inferior to Natural Immunity

The COVID-19 modRNA shot delivers only the genetic information for the Wuhan sequence of SARS-CoV-2 virus. Natural immunity will create cross-immunity, which is protection against mutations of the virus. The shot, on the other hand, can only hope to provide specific protection to the Wuhan version (not the Alpha, Beta, Gamma, Delta, Omicron, ... variants) and cannot recognize any other mutation. The virus mutates far quicker than the time it takes for the pharmaceutical industry to create and distribute their shot to billions of people on the planet. Thus, the antibodies produced in our bodies are always based on old viruses no longer active. Natural immunity does not depend on one viral sequence, but generates antibodies against other glycoproteins on the virus—like the nucleocapside protein. This results in far greater and more powerful immune protection.

Problem: Dangers of Redundant Proteins

Proteins represent our body's building blocks and are central to cellular metabolism. For a functional metabolism, only essential proteins can be present in a certain cell at a specific time. Proteins that are not required must be absent or they will disrupt the smooth running of the cell. Proteins or mRNAs in healthy cells are like musicians in an orchestra and play their instrument in a certain way at a certain time. Otherwise, it is chaos and cacophony. Because synthesized modRNAs were developed for longevity and have access to all cells, they contradict the nature of true mRNA which is short-lived and cell-specific. This makes modRNA a persistent danger to normal, healthy cellular metabolism. It would be like giving an orchestra member a large kettle drum to bang anytime without regard to the arrangement of the musical score. 

Problem: Increased Errors While Making the Synthetic Spike Glycoprotein

To stabilize the modRNA, synthetic methyl-pseudouridine was used to replace the natural uridine in the chain of amino acids and glycans (sugars) making the synthetic spike glycoprotein. This one substitution increases the transcriptional error rate to one error every 4,000 nucleotides or once in every synthesized vaccine molecule. The spike glycoprotein is not even built according to design! If you can't build it right, it definitely won't function right!

Problem: Active Ingredients Vary Immensely by Different Batches

The permitted tolerance level of the active ingredient in the modRNA vaccines ranges in concentration from 0.37mg/ml to 0.63 mg/ml as shown in the European Medicines Agency (EMA) Assessment Report. Such a high variation is highly unusual for a drug. In addition, a 3.4 fold variation of the active ingredient is allowed between different batches. This means that some batches have little active ingredient and few side effects, while others can have much higher levels of active ingredient and cause excessive side effects. One dose of Pfizer's COVID-19 vaccine represents 0.3 ml with 30 micrograms of active substance. This means that 13 trillion modRNA molecules are being transferred into your body with each single injection.  

Problem: This Lab-created modRNA is Incorporated Into the Human Genome

The political narrative insisted that these shots would not alter the human genome. The government spokespersons stated that "COVID-19 vaccines do not contain reverse transcriptase," thereby entirely precluding modRNA being written back into human DNA. Two publications have totally refuted this and proven that it happens. It has been known for years that 8% of the human genome does not come from our ancestors—it comes from retroviruses which have the capability of rewriting their RNA into our DNA. This is not an uncommon occurrence, but for the first time we are allowing the rewriting of a foreign, artificial, lab-created instruction. We are playing God with our biology and we have no idea what repercussions we are causing.

Synopsis of How the COVID-19 Shot Works

1. After the LNP enters the cell via endocytosis, modRNA is released. 
2. The modRNA encoding the SARS-CoV-2 spike glycoprotein is translated and synthesized
3. The spike glycoprotein is presented at the cell surface (glycocalyx) and serves as a foreign antenna that the immune system will recognize and create neutralizing antibodies for.
4. Due to the presence of a furin cleavage site, subunit-1 (S-1) can be cleaved from subunit-2 (S-2) on the spike glycoprotein and distributed throughout the body via blood and lymphatic channels
5. There is evidence that modRNA can be reverse-transcribed into DNA and incorporated into the genome of the recipient cell. This alters your human genome forever. 

Bottom Line

The modRNA forces perfectly healthy cells to produce a viral glycoprotein, transforming them from friend to foe. Therefore, RNA-based injections are not vaccines at all, but genetic manipulations—and that certainly challenges the political narrative. Numerous adverse events and deaths are already painfully obvious and this shifts the cost-benefit ratio of RNA-based vaccine technology for mass application definitely into the negative side. 

Here is a great link Lynda sent me documenting hundreds of health professionals warning the public about the dangers of vaccination.